PIWI IS REQUIRED TO LIMIT EXHAUSTION OF AGING SOMATIC STEM CELLS

Piwi Is Required to Limit Exhaustion of Aging Somatic Stem Cells

Sophisticated mechanisms that preserve genome integrity are critical to ensure the maintenance of regenerative capacity while preventing transformation of somatic stem cells (SCs), yet little is known about mechanisms regulating genome maintenance in these cells.Here, we show that intestinal stem cells (ISCs) induce the Argonaute family protein Piw

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Journey of Limonene as an Antimicrobial Agent

Injudicious consumption of antibiotics in the past few decades has arisen the problem of resistance in pathogenic organisms against most antibiotics and antimicrobial agents.Scenarios of treatment failure are becoming more common in hospitals.This situation demands the frequent need for new antimicrobial ND Filters compounds which may have other me

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Comparative Analysis of Clinical Severity and Outcomes in Penetrating Versus Blunt Traumatic Brain Injury Propensity Matched Cohorts

Traumatic brain injury (TBI) is a global health challenge; however, penetrating brain injury (PBI) remains under-represented in evidence-based knowledge and research efforts.This study utilized data from the Trauma Quality Improvement Program (TQIP) of the National Trauma Data Bank (NTDB) to investigate outcomes of PBI as compared with clinical-sev

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